Disorders of the Immune Response

Disorders of the Immune Response

The Pathophysiology of Allergic Rhinitis

Allergic Rhinitis

Allergic rhinitis is an irritation and swelling of the nasal passages, typically related with itching of the eyes and nose and watery nasal discharge. It is cause by exposure to allergens due to reaction.

IgE-mediated hypersensitivity is characterized by four cardinal symptoms:

• Runny nose

• Itching

• Congestion

• Sneezing

Your nose contains structures that capture various particles, which when accumulated in large quantity, are eliminated by reflecting outside sneezing through cholinergic terminals stimulated by the autonomic nervous system. By cholinergic stimulation of mucus production and vasodilatation increases nasal congestion generation while ...