[The Benefits of Vitamin-D as A Medical Transporter]

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ACKNOWLEDGEMENT

I would take this opportunity to thank my research supervisor, family & friends for their support & guidance without which this research would not have been possible.

DECLARATION

I, [type your full first names & surname here], declare that the contents of this dissertationper thesis represent my own unaided work, & that the dissertationper thesis has not previously been submitted for academic examination towards any qualification. Furthermore, it represents my own opinions & not necessarily those of the University.

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ABSTRACT

Vit D - also called the "sun-shine Vitamin" as the human body produces the Vit once it is exposed to the rays of the sun. A quarter of an hour of sunshine around three to four times per week is sufficient to generate the body's need of Vit D . Still, many persons living in sunny climates still do not make sufficient Vit- D & need more from their food intake or supplementation. There are various effects of the said vitamin on human body as evident by a number of studies. As a trans-criptional regulator of bone matrix proteins, itleads to the absorption of osteocalcin & suppresses synthesis of type I collagen(Ginde et al. 2009 ). In cell structures , Vit- D genreates differentiation of osteoclasts. Still, experiments on animals and homo sapiens Vit- D insufficiency or mutations in the Vit- D receptor lead to conclusions that the effects donot lead to of any important physiologic change , & that the critical effects of Vit- D on bone are to ensure proper proportion of of calcium(cacl2) & phosphorus in the body to support mineralization. The following presents strong arguments about the advantages of vit D in cases of diseases associates with the shortage of serum, 25(OH)D . there has been more research for diseases that are more common and serious in nature. Bone Vit - D has been proven effective in a variety of. As a trans-criptional regulator of bone matrix proteins induce the expression of osteocalcin and type I collagen synthesis inhibition .In cell culture, Vit - D that stimulates the differentiation of osteoclasts. Still, humans and animals, Vit - D, or the lack of variation Vit - D receptors in the study of these effects, the meaning of the main physiologic does not ahmadodoe & Bone Vit - D major effect was to provide a proper balance to We recommend cacl2 and phosphorus to support mineralization.

Table of Contents

ACKNOWLEDGEMENTII

DECLARATIONIII

ABSTRACTIV

CHAPTER 1: INTRODUCTION TO VITAMIN D1

1.1Structure & Synthesis1

CHAPTER 2: SIGNIFICANCE OF VIT- D : LACK OF VIT- D IN ELDERLY PERSONS LATELY4

3.1Tumor7

3.2Heart ailments9

3.3DMII mellitus9

3.4Infectious ailments10

3.5Severe liver or kidney ailment11

3.6Other Vit D -sensitive ailments11

CHAPTER 4: HOW IT'S TRANS-PORTED INSIDE THE BODY13

4.1The Vit- D Receptor & Mechanism of Action13

CHAPTER 5: REACTIONS INSIDE THE BODY15

5.1Method of Action15

5.2Toxicity Levels16

CHAPTER 6: DOSAGE17

6.1Recommended Dietary Allowances17

CHAPTER 7: CASE STUDIES19

REFERENCES21

APPENDICES28

CHAPTER 1: INTRODUCTION TO VITAMIN D

Structure & Synthesis

The term Vit- D is, an inexact term referring to one or more members of a group of steroid molecules. Vit D3, also called chole-calciferol and ...