SUMMARY

Summary: Chapter 18

Summary: Chapter 18

The term chronic lymphocytic leukemia (CLL), integrates heterogeneous in their clinical, morphological and immunological characteristics of the disease nature of the tumor, based on the development of which is monoclonal proliferation of abnormal lymphoid elements.

Diagnosis

Most cases of this disease - B-cell form. Abnormal lymphoid elements in this disease come from the same precursor cells; most of them contain cytoplasmic immunoglobulin monoclonal. In CLL B cells do not differentiate to form plasma cells that produce immunoglobulin, so patients with severe infections occur, is often the cause of death. In addition to the violation of the antibody in ...