EXPERIMENT-4

Experiment 4

[Name of the institute]Experiment 4- PARTITION COEFFICIENT AND PKa OF ASPIRIN

Introduction

In order to create a biological reaction, a molecule of drug will have to come through extensively lipid biological membrane. For a drug, it is quite essential to develop a needed correct balance between the polar and non-polar groups, that is, hydrophilic and hydrophobic. In normal cases the drugs with their polar tendency remain in the bloodstream. On the other hand, the ones that are non-polar are absorbed within and stay inside lipid interior of the membranes. In either cases mentioned above, the main focus shed the light on drug ...