DRUGS

Drugs

Drugs

Introduction

Drugs are natural or synthetic substances that cause effects when you use your body and mind. These effects can be permanent and cause changes in your feelings and your behaviour. The drugs cause changes in the parties 'p': thoughts, person perception.

Drugs are substances, which excludes the "Drug Abuse" behaviours such as compulsive gambling, watching too much television, video games, etc. However, these behaviours are likely to cause addiction.

Both legal and illegal, in fact, the most consumed drugs in our society, causing more problems, are the snuff and alcohol, whose use is permitted. For this reason, prevention, when dealing with substances, should insist mainly on snuff and alcohol is not underestimating the risks of consumption.

It does not specify the route, because the drug can be ingested such as alcohol and drugs, either as snuff and smoking marijuana, others can be given by intravenous (injected) or some also can be inhaled through the nose, etc.

The changes do not occur exclusively to psychological or physical level, but also alters the environment, the workplace, and to study the system of values and beliefs of the individual. We can conclude as to what are the drugs that any substance that alters the normal parameters of life of the individual who consumes drugs is considered, whether lawful or not. Not necessarily have to consider only those drugs classified as illegal or prohibited, as are or contain drugs addictive drugs and alcohol are the components of snuff (nicotine) and caffeine in coffee, tea or soft drinks tail.

"Drug" is any substance which, introduced into the body by any route of administration produces an alteration of the natural functioning of the central nervous system of the individual and is also capable of creating dependency, whether psychological, physical or both.

Discussion

The application to finding new indications for existing drugs was highlighted by Boguski, Mandl, and Sukhatme (2009). The authors call this goal "repurposing" and propose that it can play a major role in the "major overhaul of the R&D paradigm" (p. 1394) that many believe is needed in the drug industry. Past examples include successful "off-label" uses of drugs discovered by serendipity or, in some cases, using knowledge about the biological pathways and mechanisms of drug effects and diseases. Because of our increasingly sophisticated understanding of human biology and the molecular pathways of disease, one would expect there to be increasing opportunities for expanding off-label use based on fully elucidated pathways and mechanisms of action, a situation that has been called a 'new grammar of drug discovery.' (p. 1394)

This focus was driven by a set of queries, applications, and information needs (Appendices A-B) that reflect the needs of specific user types - consumers, clinicians (physicians, nurses, etc.), pharmacists, and biomedical researchers - known to us through decades of study and professional experience. Examples include: finding equivalent drug names (e.g., generic name version of a brand name, or the chemical name of the active ingredient); finding alternative drugs for a given indication or vice versa; identifying ...