BIOLOGICAL INVESTIGATION OF NANOMATERIALS

Biological Investigation of Nanomaterials

Biological Investigation of Nanomaterials

Multifunctional Nanodevices And Imaging

One of the promises of medical nanotechnology is a drug-delivery nanodevice that can likeness, goal, and deliver drugs to a exact cancerous disease location inside the body and supervise and if necessary adapt the pharmaceutical issue at the goal location. Researchers in Taiwan have now conceived a nanodevice that comes pretty close to this vision. "We have effectively illustrated that our multifunctional drug-delivery nanodevice - a polymer core/single-crystal iron oxide case nanostructure bonded to a quantum spot - can likeness, goal, and consign pharmaceuticals via isolated control," Dean-Mo Liu, a lecturer in the Nano-Bioengineering Lab at nationwide Chiao Tung University, tells Nanowerk. "The apparatus displays spectacular release and keeping characteristics via an external on/off manipulation of a high-frequency magnetic field. Furthermore, the quantum spot bonded to the nanodevice provides optical data for in situ supervising of the pharmaceutical release." In preceding work described last year, Liu and his colleagues have developed a new kind of magnetic core/shell nanocapsule that allows hardworking molecules to be expelled in the occurrence of a remotely controlled magnetic field ("Core/Single-Crystal-Shell Nanospheres for Controlled pharmaceutical Release by a Magnetically Triggered Rupturing Mechanism"). There, the group has shown that the release of the hardworking substances from the nanocapsules can be fine-tuned according to exposure time in the magnetic field. "although, we thought it would be attractive to farther engineer the nanocapsules to monitor the issue of hardworking molecules at nanometric or cellular resolution," says Liu. "We furthermore accepted that a nanocapsule should be able to supply effortlessly supervised, high-resolution optical data, viewable by simple spectroscopic procedures, rather than conventional MRI imaging."

Biosafety / Toxicology of Nanomaterials

Nanotechnologies are expected to offer a wide range of economic advantages. However, unlocking this potential will need a to ...