THE FUTURE OF PERSONALIZED MEDICINE

The future of personalized medicine

The future of personalized medicine

Introduction

Personalized medicine is a medical model emphasizing in general the customization of healthcare, with all decisions and practices being tailored to individual patients in whatever ways possible. Recently, this has mainly involved the systematic use of genetic or other information about an individual patient to select or optimize that patient's preventative and therapeutic car.

The Human Genome Project represents only the initial data collection: the photograph of the genes of healthy people. Now try to understand the genetics of disease, to know what happens when we are damaged DNA, and also define the characteristics that protect us or make us more sensitive to certain problems or certain drugs. Having this information allows us to take the next step in the evolution of healthcare: personalized medicine. The person can use the personalised medicine to avoid side effects. (Yoshiaki, 2005)

Technologies of personalized medicine

There are various technologies that are related to personalized medicine. However the three most common are pharmacogenomics, Pharmacoproteomics & metabolomics

Pharmacogeonomics

Pharmacogenomics is the science that studies the result of a variation in the genome of an organism and its response to a drug specific. Its purpose is to study the genes that influence the activity, toxicity and metabolism of a drug, and thus provide the information needed to prescribe a dose treatment more effective, less toxic and also specific to each patient. Pharmacogenomics seeks to define whether the expression of gene related to the effectiveness of a drug case in the enzymes responsible their metabolism, proteins related to the availability of the substance.

Pharmacogenomics researches the determination of individual differences in drug response to genetic factors. Its main objective is to study genes and their activity, toxicity, metabolism and drug reactions, plus the way of justice and the specific provisions of the stock STI treatment doses and less toxicity for each patient. Pharmacogenomics major goal is to determine whether this gene affects the sexually transmitted diseases, drug metabolism, in action website (medicine) the availability of, and through means and goals of drug binding to receptors to effect the required STD Pharmacological action (pharmacodynamics) (Lynch, 2004)

Pharmacoproteomics

Pharmacoproteomics can be defined as applied proteomic analysis to discover new therapeutic targets and to study the effects of drugs. Proteomic analysis provides insight into changes in protein expression in a biological system in response to a stimulus or function of a physiological or pathophysiological given. (Lydecker, 2002)

Metabolomics

Metabolomics is the set of sciences and techniques dedicated to the comprehensive study of the system constituted by the set of molecules that constitute the metabolic intermediates, metabolites, hormones and other signal molecules, and secondary metabolites, which can be found in a biological system. It is a term proposed by Anglo Oliver et al. in 1998, by analogy with the terms genomics, proteomics and Transcriptomics. Hodson D. (2001)

Techniques personalized medicine

One technique which might use technologies related to the personalized medicine is bioinformatics.

Bioinformatics is the use of information technology in the field of molecular ...