THE FUTURE IS PERSONALISED MEDICINE

The future is personalised medicine

The future is personalised medicine

Personalized medicine

Personalized medicine (genomics, proteomics and pharmacogenetics) is "the form of medicine that uses the information in the genes, proteins and a person's environment to prevent, diagnose and treat disease" or put another way "design and implementation strategies for prevention, diagnosis and treatment tailored to specific genetic and molecular profile of each individual and pathology” (Corbet, 2001, 100-125). Pharmacogenetics explains that individual variations in drug response may be due to the effects of age, sex, disease or drug interactions, but now is well established that many of these reactions are genetically determined.

Pharmacogenomic

Pharmacogenomics is the study of genetic mechanisms of individual variation in response to xenobiotics and, more particularly, to drugs. Pharmacogenomics aims to study the interaction between all the genes and drug once absorbed. Pharmacogenomics is based on the presence of a different response in different individuals to drug treatment. One cause of these facts is genetic (Smith, 2008, 20-40).

Pharmacogenetics

The concept of pharmacogenetics emerges from the clinical observation that patients were very low or very high drug concentrations in plasma or urine to which were then performed biochemical and metabolic evidence showing that these variations were inherited.

Pharmaco-Metabonomic

Metabonomics measures the fingerprint of biochemical perturbations caused by disease, drugs or toxins. A metabonomic study takes place in three steps: obtaining biopsies or biofluids containing the metabolic markers, the extraction of these metabolic data and to analyze data sets (Corbet, 2001, 100-125).

Metabolomics

Metabolism is simply the process of burning the body of energy and uses it. The body needs energy to live there and the basic functions, we burn energy with each heartbeat and the energy we burn with each breath we breathe, but the speed at which the body burns energy for carry out vital functions are so-called fundamental (basic metabolism).

Proteomics

Proteomics is the study and characterization of the entire set of proteins expressed by a genome (proteome). Proteomics techniques address the study of this set of proteins (Meadows, 2005, 69-75). Thus, networks can be characterized functional set of proteins and their dynamics during physiological and pathological processes.

Personalized medicine benefits

Throughout history, the practice of medicine has been largely reactive. Even today, we have to wait until the onset of disease and then try to cure them. Among cancer patients, the failure rate rises to 75 percent. Antidepressants are effective in only 62 percent of those who take them.

Personalized medicine is beginning to transform the practice of medicine. Allow health workers:

Change the emphasis on reactive to preventative medicine.

Predict susceptibility to disease, improve the detection, the progression of the disease and forestall its progression.

Customize disease prevention strategies

Technologies

The Polytechnic City of Innovation, Science Park of the Polytechnic University of Valencia, host tomorrow Tuesday, November 16, the Second Conference on Health Technology, which will focus on personalized medicine, the new challenge of public and private health.

Mass spectrometry

Spectrometry mass is an extremely sensitive detection technique for determining molecular structures. The mass spectrometer is often coupled with a system of ...