Iron is present in the body in haemoglobin, myoglobin, haemosiderin and ferritin, and in iron-containing enzymes. Transferrin is the main transport protein in blood and hepcidin the main regulator of iron absorption and iron release from macrophages. Iron metabolism is regulated according to iron status by intracellular iron regulatory proteins and by control of hepcidin synthesis. There a shortage of hemoglobin, either to a shortage of red blood cells or shortage of hemoglobin content, or to both. If there was a shortage of basic materials to build red blood cells anemia occurred. Also if, there was ...