MS is a Mendelian disease, originated by a single flawed genetic material (either dominant or recessive). No other genetic or environmental issues need to be in attendance in order for MS to develop in an affected person. Primary indication that a disease is Mendelian often comes in the form of identifiable inheritance prototypes; final proof is provided by the identification of a gene that segregates cleanly with the disease in affected families. In MS, none of the typical Mendelian pedigree patterns have been consistently found in studies of multiplex families.
While it is possible that familial evidence collected to date has ...