Summary 26

Summary 26

Summary

It is not necessary that coagulation diseases are not always acquired; they are also inherited in various cases. Haemophilia A is the most common inherited deficiency of a clotting factor. It is severe if factor VIII activity in plasma is <1% of normal. It presents with excess bruising or prolonged bleeding after trauma and spontaneous bleeding, usually into muscles and joints, which can result in joint deformity. Infants may develop profuse post-circumcision haemorrhage or bleeding in soft tissues and joints. In addition to this, excessive bruising occurs when infants start to be active. Recurring and painful muscle haematomas and ...