SICKLE CELL ANEMIA

SICKLE CELL ANEMIA

SICKLE CELL DISEASE

Introduction

Sickle cell disease is a genetic disorder which means it's transferring by generation to generation it is characterized through the defective hemoglobin, i.e. a protein presence in the red blood cell and performs a function to carry out Oxygen to the different parts of the body.

Red blood cells or hemoglobin proteins are particularly involved in the Sickle cell disease, those effects on the ability of them to carry out the oxygen. Like a letter “O” the hemoglobin cells are flexible, smooth, and round, that structure provides feasibility to move by the thin vessels of our body easily. Like a letter of “C” Sickle cell hemoglobin cells are inflexible, humid and rigid, and appearance into the shape of a sickle, while they lost their ability to carry Oxygen. These are tried to develop clusters and been apt together that create the difficulties to move throughout the blood vessels. Consequences these clusters are caused a blockage and discontinue the supply of the normal and healthy amount of the oxygen to the different tissues. That leads the damaging and painful impediments of the sickle cell disease.

These cells are only alive for the period of the 15 days, although a normal healthy hemoglobin cell is alive for the period of the 120 days. Also Spleen may destroy the risk of the sickle cells for the reason of the rigidity and their shape. Spleen is an organ of the body that helps in blood filtration from the infections, while sickle cells are caught by the filter, they stuck and finally die. Because of the insufficiency of the hemoglobin cell as it changed in to the sickle cells, the individual gets a chronic anemia. Spleen is also suffered because of the blockage of the sufficient amount of the oxygen which is carried by the sickle cells. These individuals are come at the high risk because of the abnormal functioning of the spleen. And the adolescence and the infants are at the risk of the death. (Hankins, Jeng & Harris, 2007)

The chronic aspect of the SCD is included the chronic infections, stroke, damaging tissues and cardio vascular diseases. The probability and the possibility of attack of these chronic aspects may rise with the increase of the age factor. In the United State of America, SCD is commonly seen in the African-American. As it has been recorded according to the present estimations, one out of twelve kids is being born with the trait of the SCD. And one out of six hundred (600) black kids is being born with the sickle cell anemia. The other people are being suffered with the SCD are commonly come from the families of the Africa-American as their ancestor were black.

Note: It is not necessary that the parents are suffered with the SCD, they just have the traits of the SCD and these traits are transferred to their offspring. If both parents have the traits of the SCD then there is a 25% chance that the ...