HELA CELL

HeLa cell

HeLa cell

HeLa cell and its importance

HeLa cells (HeLa line, HeLa cell line) was produced by human epithelial cells, a cervical carcinoma (cervical cancer) and it was the first human cell from which a permanent cell line was established. On 9 February 1951 surgeon Lawrence Wharton Jr. removed this form a patient a 31-year-old African-American woman from Baltimore, in the Women's Clinic of the Johns Hopkins Hospital, some of these cells were from cancer on the cervix to see it on the malignancy of the patient and to investigate it further. Although the patient died eight months later in with tumor, but still an attempt was made. The cells were formed from human papillomavirus 18 (HPV18) affected. The gene defect could now be solved: the cells were both by a viral protein that the p53 tumor suppressor gene inactivated, and by a mutation in the HLA (human leukocyte antigen) of Supergenfamilie on chromosome 6 tumor cells to degenerate. When cells are removed from the human body they begin to die slowly and inexorably. Cells can not survive without the vital support provided by the body and can not continue artificially because of its texture and durability.

A portion of the cells from the biopsy was sent to George Gey, who was the leader of the cell culture laboratory at Johns Hopkins Hospital. The cells were cultivated and proliferated in cell culture so much that they have since been widely used in research. The HeLa cells are important because they were used in the establishment of the first vaccine against polio by Jonas Salk. HeLa cells are now in many laboratories in the world so more often that their total mass exceeds the body mass of Henrietta which lacks more than a hundred times. The demand from all over the world has ...