What is the difference in outcomes for patients diagnosed early versus late with depression while being treated for Hepatitis C?

RLRA-2 RESEARCH: LITERATURE REVIEW AND ANALYSIS

Research Proposal - Part II

Search Strategy

Data Bases (e-libraries):

Jstore

Proquest

Science direct

Sage journals

Medical Evidence Matters Archive

Natural Medicines Comprehensive Database

UpToDate

SAGE Research Methods Online

Keywords:

Depression and Hepatitis C

Diagnosis of early vs. late depression

Pre and post affects of hepatitis C

Effect of depression on Hepatitis C

Describing strategy for synthesizing the data

Preliminary Literature Search

Factors influencing longterm changes in mental health after interferonalpha treatment of chronic hepatitis C. Schmidt F, Janssen G, Martin G, Lorenz R, Loeschke K, Soyka M, Folwaczny C, Schaefer M. Aliment Pharmacol Ther. 2009 Nov 15;30(10):104959. doi: 10.1111/j.13652036.2009.04123. x. Epub 2009 Aug 18. PMID: 19691667 [PubMed indexed for MEDLINE]

Interferon for hepatitis C patients with psychiatric disorders. Asnis GM, De La Garza R, Rego SA, Henderson MA, Reinus JF. Am J Psychiatry. 2004 Dec;161(12):2332; author reply 23324. No abstract available. PMID: 15569920 [PubMed indexed for MEDLINE]

Response to interferonalpha of Egyptian patients infected with hepatitis C virus genotype 4. elZayadi A, Simmonds P, Dabbous H, Prescott L, Selim O, Ahdy A. J Viral Hepat. 1996 Sep;3(5):2614. PMID: 8914006 [PubMed indexed for MEDLINE] [Hepatitis C viral infection and depression]. Lengyel G, Aszalós Z, Tulassay Z. Orv Hetil. 2007 Jan 7;148(1):115. Review. Hungarian. PMID: 17344112 [PubMed indexed for MEDLINE]

Psychiatric implications of hepatitisC infection. Giunta B, Somboonwit C, Nikolic WV, Rrapo E, Tan J, Shapshak P, Fernandez F. Crit Rev Neurobiol. 2007;19(23): 79118. Review. PMID: 19409058 [PubMed indexed for MEDLINE]

Prophylactic SSRI during interferon alpha retherapy in patients with chronic hepatitis C and a history of interferoninduced depression. Kraus MR, Schäfer A, AlTaie O, Scheurlen M. J Viral Hepat. 2005 Jan;12(1):96100. PMID: 15655055 [PubMed indexed for MEDLINE]

Can antidepressants prevent interferonalphainduced depression? A review of the literature. Galvãode Almeida A, Guindalini C, BatistaNeves S, de Oliveira IR, MirandaScippa A, Quarantini LC. Gen Hosp Psychiatry. 2010 JulAug;32( 4):4015. doi: 10.1016/j.genhosppsych.2010.03.001. Epub 2010 Apr 2. Review. PMID: 20633744 [PubMed indexed for MEDLINE]

Major depression during interferonalpha treatment: vulnerability and prevention. Lotrich FE. Dialogues Clin Neurosci. 2009;11(4):41725. PMID: 20135899 [PubMed indexed for MEDLINE]

Treatment of major depression: selection of initial drug. Potter WZ, Schmidt ME. Mod Probl Pharmacopsychiatry. 1997;25:116. Review. No abstract available. PMID: 9344366 [PubMed indexed for MEDLINE]

Continuation treatment with antidepressants in child and adolescent major depression. Ryan ND. Am J Psychiatry. 2008 Apr;165(4):4112. doi: 10.1176/appi.ajp.2008.08010115. No abstract available. PMID: 18381908 [PubMed indexed for MEDLINE]



What is the difference in outcomes for patients diagnosed early versus late with depression while being treated for Hepatitis C?

Introduction

Hepatitis C is caused by a virus spread primarily by contaminated blood, but the infection can also pass through the roads sexual and vertical (mother to child). The carrier of hepatitis HCV may develop a chronic form of the disease that leads to liver damage (cirrhosis) and liver cancer. Hepatitis C is asymptomatic in most cases, ie the wearer feels nothing after virus infection (Bruce, 2007). In some situations, there may be an acute form of the disease ...