The physical benefits of using origami

The physical benefits of using origami

Introduction

Life and Nano sciences advancement in tandem with developments of high resolution imaging procedures and methods. All through the last decades, the improvement and invention of scanning probe microscopy methods and procedures like AFM (Atomic Force Microscopy) have presented new ideas onto nano-scale materials (Castro et al, pp. 221-229). Optical microscopy has been reached ahead of the diffraction limit and the inspection of single molecules has grown into a standard technology. The proposal seeks support of fabrication of DNA scaffold based nano-scale antennas. Advances in nanotechnology and drug delivery mechanisms paired with the molecular biology, and DNA origami techniques lead to evolution of new breed of nano-electronics (Fries, et al). The focus of our research is the development of nano-scale antenna using configurable DNA structure as a template. Although chemical and electrical characteristics of DNA are limited in functionality, DNA can be used as scaffold for functional building material. Such a structure could be covered with a dense coating of ~5-7 nm diameter metal nano-particles, and studied as an antenna (Fumeaux et al, pp. 123-183).

Benefits of Using Origami

Nano lenses that are self assembling and utilize DNA as a material for construction represent a better method of visualizing single molecules and might facilitate to unlock various biological processes such as DNA replication or transcription at the level of a single molecule. An advance self-assembling nanolens that utilizes DNA as a major material for construction may imagine single molecules (Hone et al, pp. 666-668). Here, the gray colored DNA origami nanopillar is immobilized at a cover slip. Two 40-50 nm radius nanoparticles of gold acts as a nanoantennae and focus the light at the hot spot present in between the nano particles. Moreover, a fluorescent dye attached at the hot spots acts as an active optical basis and reports on the fluorescence development or improvement (Biercuk, M. J., et al, pp. 2767-2769).

Overlapping plasmonic fields present in between nanoparticles serve as nanoantennae in order to focus light far away from the limit of diffraction (Heckman et al, pp. 103304). Such firm focusing may enhance the sensitivity of the applications related to biotechnology. Even though various other single molecule visualization methods and techniques exist, they are expensive and complex (Haun et al, pp. 660-665). It is expected that this self assembly approach may create various nano lenses cheaply and quickly, and that the procedure might affect a vide range of research fields.

Correspondence between a usual and a conventional lens (shown left) focusing a beam of light and the nano lens (shown right) made with two gold spherical nanoparticles on a DNA origami pillar structure (Hone et al, pp. 339-343). Furthermore, the nanolens may concentrate the beam of light between the particles in a tremendously reduced volume (Dietz et al., pp. 725-730). There are usually two application fields, one involves more basic research on nanophotonics and plasmonic, in view of the fact, with this method, dyes may be placed at a very proximity to various ...