Quantitative Critique

Topic

STUDENT NAME:

FULL AND COMPLETE REFERENCE FOR THE ARTICLE:

Nichols,L., Pike, V. W., Cai, L., & Innis, R. B. (2006) Imaging and In Vivo Quantitation of -Amyloid: An Exemplary Biomarker for Alzheimer's Disease? Biol psychiatry 2006;59:940-947 941. Retrieved from http://intramural.nimh.nih.gov/mib/radio/pubs/radiopub2006-06.pdf

What is the problem the study was conducted to research?

Alzheimer's disease is accompanied with ß-amyloid that infests the brain. This leads to further complications and hence a cure to this issue is necessary to cure Alzheimer's disease.

Why is the problem an important one for nursing to research?

This disease is characterized by various effects such as memory loss, depression, and anxiety. Therefore, it is important to determine a cure for this disease.

What is the purpose of the study?

The purpose of this study is to explore the possible use of amyloid and positron emission tomography in order to diagnose and treat Alzheimer's disease. The use of magnetic resonance imaging is also explored as a possible means of diagnosing AD.

What is the main research question?

The main question of this research is whether or not Amyloid is a useful Biomarker to diagnose and treat Alzheimer's disease.

What is the study hypothesis? If it is not stated, what would you say the hypothesis is?

The hypothesis of this study is that Aß is a possible means to diagnose and cure Alzheimer disease.

Identify and describe the major study variables. Identify the study variables by examining the purpose, the objectives, questions, or hypotheses, and the results section of the research article.

The major variables are the presence of Aß40 and Aß42 in patients diagnosed with Alzheimer's disease.

Define the meaning of the term “independent variable

Independent variables are those variables whose values are not dependent on the values of other variables. In this research, the independent variables are amyloid plagues are considered the independent variable since this is the main component of this diagnosis and is not related to the outcomes of the study.

Identify the independent variables in this study and provided a definition of the variable.

Pittsburg compound 'B' (PIB) is one of the independent variable important for this study.

How is the independent variable carried out in this study?

The independent variables are analyzed in patients and related to that found in other patients in other to form a correlation.

Define the meaning of the term “dependent variable.”

Dependent variables are those whose value is dependent on the value of another variable. In this study, the dependent variable is the treatment of AD.

Identify the dependent variables in this study and provide a definition of the variable.

This is the dependent variable because other variables are studies and manipulated in order to find a cure for this disease. Thus the results of this study will conclude on the treatment of Alzheimer's disease.

How is the dependent variable measured in this study?

The dependent variable is measured by observing patients in some hospitals for a few days and analyzing their condition and behavior.

Is the framework explicitly expressed or must the reviewer extract the framework from implicit statements in the literature review? JUSTIFY your response!

The ...