NON-LEUKAEMIC MYELOPROLIFERATIVE

Non-Leukaemic Myeloproliferative Neoplasms

Non-Leukaemic Myeloproliferative Neoplasms

Introduction

Myeloproliferative Neoplasms is a condition that emerged from the marrow stem cells. Clonal proliferation is a component in the bone marrow and in several cases it is present in the spleen and liver, as well. The Non-Leukaemic disorders are classified as follows:

1Polycythaemia vera (PV);

2Essential thrombocythaemia (ET); and

3Primary myelofibrosis.

Discussion

The Non-Leukaemic Myeloproliferative disorders are related to each other very closely. Such diseases are characterised by clonal abnormalities. Another element discussed in the chapter is Polychythaemia. This is an increase in the level of haemoglobin that is above the limit for the patient's sex and age. This is ...