Member of the immunoglobulin superfamily of glycoproteins secreted by mature vertebrate B cells, binding selectively to epitopes of antigens and clumping them (agglutination) prior to phagocytic engulfment. Antibodies travel via the lymph to the blood, and viruses coated in antibody cannot enter host cells. In humans, antibodies in breast milk are not absorbed into the baby's blood but only act in the gut; but in cattle they are absorbed into the calf's blood by pinocytosis (Collard, 2006).
Five major classes differ principally in their type of heavy protein chain, and the degree to which the molecule is a polymer of immunoglobulin ...