Effect Schizophrenia due to neurotransmission

Effect Schizophrenia due to neurotransmission

Schizophrenia is found among one percent of the overall United States population. This shows that more than three million people in US are suffering from this disease. Schizophrenia is a disorder that leads to different unusual behaviors in the life of person that not only disturbs the life of the person but also the people around them. This disease can be found in any person without regard to age, gender and social discrimination (Lewis, et.al, 2004).

The article written by Nauert focuses over the increasing risk of schizophrenia due to excess neurotransmission in brain. The excess neurotransmitter can also cause the psychosis. The research conducted by the scientists of Columbia University of Medical Center believes that the research on this issue can help the people who are at risk of schizophrenia. The experts also believe that glutamate limiting treatment strategy and slow progression of schizophrenia are related to each other and are almost similar disorder. Glutamate is one form of neurotransmitter whose excess transmission leads to the development of schizophrenia.

Neurotransmitters are regarded as effective messengers of the brain that carry signal from one part of the brain to another part. Experts observe the communication process with in the brain to analyze the difference between the brains of people having schizophrenia to the brains not having this disorder. Studying neurotransmitter can effectively discover the functional and structural differences within the brain (Valenzuela, et.al, 2011).

In the article, the research of Schott Small is taken in to account according to which the patients having schizophrenia disorder are observed with changes in hyper metabolism and atrophy of the brain. The research further reveals that these changes of the brain are observed early in the disorder, these changes affect the functionality f the brain and these changes can be observed before the development of the disease. Neuroimaging tools are used to observe the neurotransmission of the brain. The researchers used to the neuroimaging tools to observe the neurotransmission of both human and mouse.

To observe the structural changes in the brain due neurotransmission research was conducted among the group of twenty five people. These people were assumed to be at the risk of schizophrenia. The motive of the research was to observe what changing's takes place in the brain with the people who develop with this disease. The results revealed from the research shows that the patients that are likely to adopt this disorder have different changes in this mind. Initially the glutamate activity increases in the brain, which increases the metabolism of the hippocampus after that hippocampus leads to atrophy.

To further observe that schizophrenia takes place due increase in glutamate, the researcher turned to the mouse model of schizophrenia. When the glutamate activity was increased tin the mouse, the same changes were observed in the brain of the mouse and same patterns in were observed that were observed in the patient.

The glutamate activity of the brain can be observed by the neuroimaging in a patient and ...