Drug Information assignment

1-In what dosage form is Lipitor available? (Select all that apply)

Select one or more:

a. capsule

b. tablet

c. lotion

d. solution for injection

2-What is the correct initial dose of irbesartan for a 15-year-old patient with hypertension?

Select one:

a. 450mg/day

b. 300mg/day

c. 150mg/day

d. 25mg/day

3- If clonidine and desipramine are given together what drug interaction may occur?

Select one:

a. no interaction occurs

b. clonidine effects may be decreased

c. clonidine effects may be increased

d. desipramine effects may be decreased

e. desipramine effects may be increased

4-In what strength(s) is Prevacid available?

Select one:

a. 10mg

b. 20mg

c. 30mg

5-Are theophylline and linezolid compatible at the Y site?

Select one:

a. Compatible

b. Incompatible



6-What are current recommendations regarding the use of Singulair in women who are breastfeeding?

Select one:

a. It is safe for use.

b. It is not safe for use.

c. Until more information is available caution should be used.

7- The clinical study conducted by Boerner, et al and published in Phytomedicine in 2003 used a Answer blind study design.

8- Copy/paste the abstract and indexing information for a case report of phenytoin causing hepatotoxicity

A 55-year-old woman was hospitalized for treatment of community-acquired pneumonia. Unexplained, moderate elevations in hepatic transaminase and enzyme levels prompted review of her drug regimen. She had taken acetaminophen 1,300-6,200 mg/day during the hospitalization. She also received phenytoin for posttraumatic seizures. Acetaminophen was discontinued, and the patient's liver chemistries returned to normal within 2 weeks of discharge. Acetaminophen is metabolized in part by cytochrome P450 (CYP) 2E1, and inducers of CYP2E1 are known to predispose patients to acetaminophen-related hepatotoxicity. Phenytoin induces CYP2C and CYP3A4 isoforms, but not CYP2E1. The literature suggests, however, that CYP3A4 may participate in acetaminophen metabolism to a greater extent than previously realized, and induction of this isoform may predispose patients to acetaminophen-induced hepatotoxicity.

9-What is the PMID for a phase III clinical trial of zoledronic acid by M Dong published in March 2008?

The PMID for the ...