DATAANALYSIS

Data Analysis: Lab Testing of New Medication on Rats

Data Analysis: Lab Testing of New Medication on Rats

A total of 14 rats were taken as subject in the analysis. Medication test on few rats resulted in the occurrence of abnormal conditions. Some rats died during the testing phase of medication due to which sample size was kept limited to less than 30. It is necessary to consider the impact of new drug medication test on living organism physical condition. Sample size was reduced to 14 rats to estimate the impact of new medication test on wide-scale applicability. In order to improve the reliability of the data, while minimizing the possibility of negative event occurrence, t-statistics distribution technique was applied to analyze the data. Following acclimatization to the testing conditions, behaviour latencies were determined. Multiple approaches were taken to analyze the lab testing of medication on rats. In first stage, test results were conducted on treated rats, followed by conducting drug test on controlled rats.

Rats were categorized into two segments based on the body segment included in the analysis. Segments were categorized on the basis of spinal cord segmentation of the rats. Spinal cord was divided in two segments based on the lumbar area, and thoracic region. However, data was compared with the average changes in the rat structure and impact of the new drug medication on the overall physical condition of the rats. Therefore, data analysis has been combined for the overall impact of the medication on rats. Principal component analysis technique was applied to determine the component factors that have maximal impact of medication. Two groups of rats were included in the study to determine the comparative impact of new medication on rats. Controlled rat groups did not receive any other medical treatment for the recovery from spinal cord problems except only new medication test. However, treated rat groups experienced new drug medication under laboratory environment to increase the viability of test results.

A total of 14 rats were included in the study. Treated and control group of rats were medically examined to determine the impact of medication test on the axonal degeneration, number of surviving cells within a certain area of the body region, occurrence of inflammation due to new medication, and clinical behaviour changes in rats. These rats were randomly assigned to dose groups of treated and controlled group. Dose levels were chosen to provide approximately equipotent levels of the test compounds with the highest dose approaching toxicity. Sequential changes of the new medication were examined based on the factorial component structuring of the treatment regimen. Inferential statistical test were applied to achieve quantitative recovery of the new medication test on control and treated group of rats. PCA (principal components analysis) test were conducted in under optimal and linear conditions. Two groups of rats were taken as independent sample to determine the threshold changes in the impact of new medication on rats.

Standard deviation was comparatively lesser of new medication technique on axonal degeneration in treated rats ...