ASSIGNMENT

Assignment



CHAPTER4: DISCUSSION &ANALYSIS

Introduction

Previous study has shown that there is a relationship between red blood cells turnover and the use of HbA1c for monitoring diabetes but the project is to look at what effect will slight variation in red cell lifespan and iron status will have on glycaemic control within a healthy population.

The primary outcome measure is to establish the effectiveness of using certain diabetes markers such HbA1c with a view to quantifying reference levels for iron deficient Type 2 diabetes. The findings present the statistical analysis which quantifies the strength of the interdependency between two sets of measures i.e. haematological parameters (which are Full blood count, Reticulocytes, and Haematinics (i.e. B12 & folate, Ferritin) and glycaemic laboratory markers (which are HbA1c, Serum fructosamine, Fasting blood glucose).

Cross tabulations and Correlation Analysis

Type of Diabetes Mellitus * Gender

Crosstab

Count

Gender

Total

Male

Female

Type of Diabetes mellitus

T1DM

28

26

54

T2DM

111

76

187

Total

139

102

241

The above table and cluster bar chart indicates that there were huge populations of males i.e. 111 are suffering from Type II of Diabetes mellitus. There were 76 females in our sample who are suffering from Type II of Diabetes mellitus. Whereas there was a little proportion of population from both genders was suffering from Type I of Diabetes mellitus. So it can be said that most of the population are suffering from Type II of Diabetes mellitus.

Symmetric Measures

Value

Asymp. Std. Errora

Approx. Tb

Approx. Sig.

Interval by Interval

Pearson's R

-.063

.065

-.981

.327c

Ordinal by Ordinal

Spearman Correlation

-.063

.065

-.981

.327c

N of Valid Cases

241

a. Not assuming the null hypothesis.

b. Using the asymptotic standard error assuming the null hypothesis.

c. Based on normal approximation.

The above table presents the correlation analysis among the gender and type of diabetes mellitus. The value of Pearson correlation is -0.063 which indicates that a weak correlation exists among the two variables. It can be said that the individual either male or female can suffer from type of diabetes mellitus.

(sTFr) levels to detect iron deficiency in type 1 diabetic (Binned) * Gender

Crosstab

Count

Gender

Total

Male

Female

(sTFr) levels to detect iron deficiency in type 1 diabetic (Binned)

1.4501 - 4.5060

113

80

193

4.5061 - 7.5620

19

12

31

7.5621 - 10.6180

1

1

2

10.6181 - 13.6740

1

0

1

13.6741+

0

2

2

Total

134

95

229

The above table and cluster bar chart presents the cross tabulation analysis among sTFr which is the levels to detect iron deficiency in type 1 diabetic and Gender. There were 113 male and 80 females respondents reported in the above table who have sTFr within the range of 1.4501 - 4.5060. It can be said that male individuals have high level of iron deficiency in type 1 diabetes.

Symmetric Measures

Value

Asymp. Std. Errora

Approx. Tb

Approx. Sig.

Interval by Interval

Pearson's R

.047

.067

.702

.484c

Ordinal by Ordinal

Spearman Correlation

.005

.066

.082

.935c

N of Valid Cases

229

a. Not assuming the null hypothesis.

b. Using the asymptotic standard error assuming the null hypothesis.

c. Based on normal approximation.

The above table presents the correlation analysis among the sTFr which is the levels to detect iron deficiency in type 1 diabetic and Gender. The value of Pearson correlation is 0.047 reported in the above table which indicates that there is a little amount of correlation exists among sTFr and gender of individuals.

Correlation Analysis

Correlations

(HbA1c) Haemoglobin in blood

Fastg

Fructosamine

Folate

(HbA1c) Haemoglobin in blood

Pearson Correlation

1

.473**

.736**

.069

Sig. (2-tailed)

.000

.000

.285

N

241

239

235

239

Fastg

Pearson Correlation

.473**

1

.450**

.098

Sig. (2-tailed)

.000

.000

.129

N

239

239

235

239

Fructosamine

Pearson Correlation

.736**

.450**

1

.247**

Sig. (2-tailed)

.000

.000

.000

N

235

235

235

235

Folate

Pearson Correlation

.069

.098

.247**

1

Sig. (2-tailed)

.285

.129

.000

N

239

239

235

239

**. Correlation is significant at the 0.01 level (2-tailed).

The correlation analysis has been presented in the above ...