ANTI AGING

Anti Aging



Anti Aging

Life extension, also known as antiaging medicine, experimental gerontology, and biomedical gerontology, refers to attempts to slow down or reverse the processes of aging to extend both the maximum and average lifespan. Some researchers in this area, and "life extensionists" or "longevists" (who wish to achieve longer lives for themselves), believe that future breakthroughs in tissue rejuvenation with stem cells, molecular repair, and organ replacement (such as with artificial organs or xenotransplantations) will eventually enable humans to have indefinite lifespans through complete rejuvenation to a youthful condition.

The sale of putative antiaging products such as nutrition, physical fitness, skin care, hormone replacements, vitamins, supplements and herbs has become a lucrative industry, with the US market generating about $50 billion of revenue each year. Medical experts state that the use of such products has not been shown to affect the aging process, and many claims of antiaging medicine advocates have been roundly criticized by medical experts, including the American Medical Association. Bioethicists question whether and how the human lifespan should be extended (Mocchegiani and Muzzioli, 1995).

Aging is an accumulation of damage to macromolecules, cells, tissues and organs. The maximum life span for humans is in excess of 120 years, whereas the maximum lifespan of a mouse, commonly used as a model in research on aging, is about four years. Genetic differences between humans and mice that may account for these different aging rates include efficiency of DNA repair, types and quantities of antioxidant enzymes, and different rates of free radical production (Mocchegiani and Muzzioli, 1995).

Average lifespan in a population is lowered by infant and child mortality, which are frequently linked to infectious diseases or nutrition problems. Later in life, vulnerability to accidents and age-related afflictions such as cancer or cardiovascular disease play larger roles. Extension of average lifespan can be achieved by good diet, exercise and avoidance of hazards such as smoking. Maximum lifespan is determined by the rate of aging for a species inherent in its genes and probably by certain environmental factors. One widely recognized method of extending maximum lifespan in organisms such as nematodes is calorie restriction. Another technique used evolutionary pressure such as breeding from only older members. Theoretically, extension of maximum lifespan could be achieved by reducing the rate of aging damage, by periodic replacement of damaged tissues, or by molecular repair or rejuvenation of deteriorated cells and tissues (Mocchegiani and Tibaldi , 1998).

Like it or not, "anti-aging" now has a number of quite different common meanings and connotations. Each is championed by a particular group or loose coalition of interests, but advocates for these groups have a way of diving into the fray without defining their terms. This makes reading about anti-aging techniques, technologies, medicine, products, and debates very confusing for the newcomer.

•For the scientific community, anti-aging research refers exclusively to slowing, preventing, or reversing the aging process. There is, as of 2010, no proven medical technology that allows this goal to be accomplished in humans - although the jury is still out ...