Alzheimer Disease

Introduction

The aim of this research paper is to discuss the Alzheimer Disease (AD) in cellular level. The Alzheimer's disease is a form of irreversible dementia and progressive that slowly destroys the memory and cognitive abilities and finally prevents the patient to carry out even the simplest of tasks. Alzheimer disease is certainly the most common form of dementia, as well as the most common neurodegenerative disease. The causes of Alzheimer's disease are not completely understood despite numerous studies and medical research. There are some individuals presenting some specific mutations in certain genes that predispose to have Alzheimer's disease, in which the same appears at an earlier time after the 30 years of age (Harry, pp. 497).

Alzheimer disease is generally steady with a slow deterioration of the disease. The course can be divided into three characteristic stages. Human nature changes over the course of the disease. Possible symptoms are suspicion, aggression, depression, anxiety, and hallucinations. At the same time, the patient loses interest in many things. The symptoms of Alzheimer's disease vary from patient to patient.

Cause and Progression of Alzheimer Disease

Alzheimer disease is defined as a degenerative process that progressively affects brain cells and eventually causes death. Although researchers have learned more about Alzheimer disease over the last two decades, they have not yet elucidated the exact cause or causes of the disease and do not know either how to stop the progression. Scientists suspect that in many cases, a combination of factors can lead to Alzheimer's disease. In the long term, Alzheimer's disease affects all aspects of life of the person such as his thinking and his actions (Katherine, pp. 5). Because each person reacts differently, it is difficult to predict the symptoms that manifest in each individual. The 10 signs of Alzheimer's disease are:

Loss of memory

Difficulties in everyday tasks

Difficulty in speaking

Disorientation and disoriented feelings

Low quality of judgment

Difficulties in abstract reasoning

Having trouble in finding things

Changes of moods and behaviors

Personality changes

Loss of sense of initiative

Alzheimer's disease eventually affects all aspects of an individual's life: his way of thinking, feeling, and acting. Symptoms vary among individuals. It is difficult to predict the symptoms that an individual present, the order in which they appear and their rate of progression.

AD is a neurodegenerative multiple central nervous systems, characterized clinically by progressive loss of short term memory and attention, and followed by the involvement of other cognitive abilities, such as language and abstract thinking, critical judgment and recognition of places or people. In the early stages of the disease, the psychological impact on the patient is devastating, and in advanced stages, it evolves to an almost absolute silence with a progressive deterioration of their motor skills which may reach a total disconnect with the environment, being unable to control simplest physiological functions (Bali, pp. 89).

The disease occurs due to widespread destruction of neurons, mainly attributed to the beta-amyloid, a protein that is deposited between neurons, which acts as a sort of glue, incorporating plaques and tangles of neurofibrillary. The disease is accompanied by a ...