Renal failure is a serious medical condition affecting the kidneys. When a person suffers from renal failure, their kidneys are not functioning properly or no longer work at all. Renal failure can be a progressive disease or a temporary one depending on the cause and available treatment options.
The kidneys are glands that are located in the abdominal region just above the pelvis on either side of the body. When functioning normally, the kidneys separate and filter excess water and waste from the blood stream. The kidneys are responsible for producing urine, which is used to flush away the toxins. The kidneys also maintain a healthy balance of fluids and electrolytes, or salt compounds, in the body.
Total Population, 1997
New Cases of End-Stage Renal Disease
Rate per Million
TOTAL
289
Race and ethnicity
American Indian or Alaska Native
586
Asian or Pacific Islander
344
Asian
DNC
Native Hawaiian and other Pacific Islander
DNC
Black or African American
873
White
218
Hispanic or Latino
DNA
Not Hispanic or Latino
DNA
Black or African American
DNA
White
DNA
Gender
Female
242
Male
348
Family income level
Poor
DNC
Near Poor
DNC
Middle/high income
DNC
Select populations
Age groups
Under 20 years
13
20 to 44 years
109
45 to 64 years
545
65 to 74 years
1,296
75 years and older
1,292
The current average annual increase in new cases of treated chronic kidney failure rates is 6 percent. Therefore, the expected rate in 2010 would be 612 new cases per million populations. Without improvements in prevention and because of changes in demographics and increases in the number of cases of diabetes, rates of new cases of treated chronic kidney failure are expected to continue to rise 5 to 8 percent per year.
Persons With Treated Chronic Kidney Failure, 1997
Deaths From Cardiovascular Disease
Per 1,000 Patient Years at Risk
TOTAL
70
Race and ethnicity
American Indian or Alaska Native
63
Asian or Pacific Islander
60
Asian
DNC
Native Hawaiian and other Pacific Islander
DNC
Black or African American
62
White
75
Hispanic or Latino
DNA
Not Hispanic or Latino
DNA
Black or African American
DNA
White
DNA
Gender
Female
73
Male
67
Family income level
Poor
DNC
Near Poor
DNC
Middle/high income
DNC
Cardiovascular disease is the major cause of death among patients with chronic renal failure and ESRD. Therefore, targeting reduction in CVD deaths will lead to a significant decrease in deaths for this population. The increased risk of CVD in kidney disease patients is evident before the onset of terminal kidney failure. Increases in the number of CVD deaths also are seen in individuals with proteinuria or elevated creatinine (both are markers of declining kidney function). CVD death rates in the treated chronic kidney failure population are estimated to be 30-fold higher than in the general population. The known risk factors for CVD in the general population include age, male gender, diabetes, elevated cholesterol, high blood pressure, smoking, and family history. Elevated homocysteine levels in the blood also may be an important risk factor in treated chronic kidney failure patients and at earlier stages in the progression of kidney disease. Strategies to reduce CVD deaths should target risk reduction before terminal kidney failure. All responsible health care providers can initiate the strategies to reduce CVD deaths as suggested in published guidelines.
Newly Diagnosed Patients With Treated Chronic Kidney Failure, 1996
Received Counseling Prior to Renal Replacement Therapy