POSTMENOPAUSAL WOMEN AND CARDIAC RISK REDUCTION

Postmenopausal women and cardiac risk reduction

Article

Information given to postmenopausal women on coronary computed tomography may influence cardiac risk reduction efforts

Critique

Cardiovascular disease (CVD) is the major risk factors through appropriate changes can be prevented. We sought to compare the heart of a comprehensive risk and without computed tomography (CT) coronary artery imaging and cardiac risk in postmenopausal women shielding effect of behavior change factors.

The fact that the proportion of cardiovascular events among all causes of male mortality is so high, it is quite logical, coronary heart disease (CHD), formerly belonged to one of the prerogatives of the stronger sex. However, the level of cardiovascular mortality in women exceeds that for men, raises serious concerns. It is known that the peak incidence of this disease occurs during postmenopausal women. In this connection it is worth examining in more detail, can there be any individualized approach to prevention and treatment of cardiovascular disease (CVD) in older women. One of the most common nosological forms in both women and men over age 40 is arterial hypertension (AH). In particular, among women after the age of overcoming this barrier hypertension incidence increases significantly, which is usually associated with changes in hormonal homeostasis? Women in this age group can be combined into a special group of high risk of hypertension. The reason is the lack of estrogen, high FSH, hormonal imbalance and relative hyper androgens. Age-related shifts of the levels of sex hormones in a woman's body help to change the constitution according to the type of abdominal obesity, the emergence of dyslipidemia, insulin resistance (IR) and impaired glucose tolerance, which ultimately leads to the formation or worsening of the metabolic syndrome (MS).

In the conduct of the patients in that age group should take into account the fact that hormones can differ significantly in the pre-and postmenopausal periods. Thus, women with hypertension in pre-menopausal, not usually observed such a high level of blood pressure, as in postmenopausal women. They are characterized by hyperkinetic type of circulation, activation of the sympathy adrenal system, expressed by vascular manifestations. Postmenopausal women more often tend predominance of growth in total peripheral resistance against the backdrop of the high activity.

Arterial hypertension (AH) remains one of the most common but potentially avoidable risk factors, providing a major contribution to the development of such serious complications as stroke, cerebral-vascular insufficiency and myocardial infarction.

Epidemiological studies conducted, suggests that hypertension is one of the most prevalent diseases. Among women aged 45-74 years, the proportion of CHD and stroke in the pattern of mortality from cardiovascular disease is 85%, and in the structure of overall mortality 45.4%. In men the same age, 87.5% of deaths occur in coronary heart disease and stroke, the proportion of these diseases in the structure of the overall mortality rate was 40.8%. According to the Framingham study, the contribution of hypertension to the risk of cardiovascular disease in postmenopausal women is significantly greater than that of men. Currently there is no doubt that patients with ...