POLYMORPHISM

Polymorphism

Polymorphism

Explain Why Polymorphism Is Important In The Pharmaceutical Company

Polymorphism is significant in the development of pharmaceutical ingredients. Many pharmaceuticals obtain regulatory acceptance for only a lone crystal pattern or polymorph. In a classic patent case the pharmaceutical business GlaxoSmithKline kept protected its patent for the polymorph kind II of the hardworking component in Zantac against competitors while that of the polymorph kind I had currently expired. Polymorphism in pharmaceuticals can furthermore have direct health implications. Medicine is often administered orally as a crystalline solid and dissolution rates count on the accurate crystal pattern of a polymorph.(Hilfiker 2006:41)

Cefdinir is a pharmaceutical seeming ...