Intervention in Diabetes

Table of Contents

Introduction3

Discussion3

Change in weight4

Change in Physical Activity4

Adherence to Medication4

Incidence of Diabetes5

The effects of treatment amongst subgroups5

Glycemic Changes6

Conclusion6

References8

Introduction

In a country like United States almost 8 percent of the individuals, mainly adults are a victim of Type 2 diabetes. Diabetes mellitus Type 2, which was previously recognized by the name of, non insulin dependent diabetes (Harris, 2001). This kind of diabetes tends to be more costly and a serious ailment for the victim. There are examining studies including two clinical trials of exercise, diet or the combination of both that elaborates the prevention of the disease in individuals, who are at the high risk for the disease. However, there are no proves or studies of drugs that were used to treat the disease. The acceptability of generalizing the outcomes of past prevention studies is yet skeptical. Interventions are not considered to be equally applicable internationally; they tend to work better in some societies, when compared to others. Large and randomized clinical trials were done in order to find out the effect of the lifestyle and its correlation with the incidence of Type 2 diabetes, with the factor of the lifestyle.

Discussion

More than three thousand randomly selected participants were assigned, out of which almost 33% was assigned to each of the groups, which included the placebo, the metformin and the ones which have intensive lifestyle intervention. Generalized characteristic including the risk factors for diabetes were kept on the similar benchmark for all of the three groups. At the final closure of the study, out of the selected sample population, around 99.5 percent participants were alive out of which 92.5 percent did a regular visit.

Almost half of the total participants, which belonged to the lifestyle intervention category, had successfully achieved the objective of weight reduction of around 7 percent. In the similar group, the daily energy intake was decreased by an average of around (450 k cal) which was quite high in comparison to the placebo group (249 k cal) and in the metformin group (296 k cal). Additionally the intake of fat, which was around 34 percent of the total calorie intake, decreased by 0.8 percent in the placebo and the metformin groups and by a large difference of around 6.6 percent in the life style intervention group.

Change in weight

As far as the change of weight is concerned, the study revealed that the subjects that belonged to the lifestyle group reduced their weight much more than the other two groups . Among those two groups the least weight was lost by the groups that were on placebo.

Change in Physical Activity

Similar to the above results, the highest responded group in this category was also the ones with the lifestyle intervention, while the other two groups responded almost similar to each other.

Adherence to Medication

As the individuals from the group of lifestyle intervention are not subject to oral medications, the other two groups were compared in this category. The result showed that the individuals on the placebo where more adherent to the medication that the ...