Although experiments on human beings has long been understood to be fraught with serious ethical problems, little has been done to develop national and international principles and rules on such research until the end of World War II. Population, often the victims of involuntary or forced participation in a potentially dangerous experiments included prisoners and insane asylum inmates. Due to popular recognition of the need for testing new therapies, the defenders of the rights of such persons found helpless little political interest in prohibiting this practice. However, the atrocities committed by Nazi doctors in ...