DRUG ABSORPTION

Describe the processes involved in drug absorption, distribution, elimination.

Describe the processes involved in drug absorption, distribution, elimination.

Although the rudimentary values ruling the absorption of pharmaceuticals from the GI tract are appreciated, numerous confounding components may play a function in modifying the method, and erratic answers may result. Some of the more significant components to be advised encompass the following:

1) molecular dimensions and form of the drug and its engrossment,

2) degree of ionization at exact pH standards (depends on pKa of the drug),

3) lipid solubility of the neutral or nonionized pattern of the pharmaceutical,

4) chemical or personal interactions with ...