BIOTRASFORMATION INDIVIDUAL DIFFERENCES IN DRUG RESPONSE.

Factors influence biotrasformation individual differences in drug response.



Factors influence biotrasformation individual differences in drug response.

Biotransformation is the process whereby a substance is changed from one chemical to another (transformed) by a chemical reaction within the body. Metabolism or metabolic transformations are terms frequently used for the biotransformation process. However, metabolism is sometimes not specific for the transformation process but may include other phases of toxicokinetics.

Biotransformation is vital to survival in that it transforms absorbed nutrients (food, oxygen, etc.) into substances required for normal body functions. For some pharmaceuticals, it is a metabolite that is therapeutic ...