H2 RECEPTOR BLOCKERS AND PPI'S

H2 Receptor Blockers and PPI's

H2 Receptor Blockers and PPI's

The first step in treatment consists of lifestyle and dietary changes. Head elevation during sleep, weight loss, avoiding certain foods, as well as cutting down on alcohol consumption and cigarette smoking help reduce the symptoms of GERD. Antacids neutralize acid in the esophagus and stomach and provide temporary or partial relief.

When GERD symptoms persist, medications such as histamine-2 receptor blockers (H2-blockers) and proton pump inhibitors (PPIs) are used to decrease stomach acid production. H2-blockers inhibit the histamine-induced acid production. PPIs block the protein that secrete acid into the stomach. ...