CHEMISTRY ASSIGNMENT

Chemistry Assignment



Chemistry Assignment

Answer C-1

During the elongation cycle, aminoacyl-t RNA, in a complex with elongation factor Tu (EF-Tu) and GTP, must bind to the ribosome carrying a peptidyl-t RNA at the ribosomal P site and deacylated tRNA at the E site (a site we found to be essential for correct and efficient translocation). EF-Tu binds to the ribosome elongation factor binding center, which is located on the 50S ribosomal subunit on its L7/L12 side. This center consists of two parts: the sarcin-ricin loop (SRL) and the GTPase-associated center (GAC). When the complex of aminoacyl-tRNA-EF-Tu-GTP binds to the ribosome, the anticodon ...